GROWTH OF INFLUENZA VIRUS IN YOSHIDA ASCITES HEPATOMA AND IN EHRLICH ASCITES TUMOR

Submicroscopic structure of Yoshida ascites hepatoma.

The electron microscope study of u ascites hepatoma cells confirms their epithelial origin. Isolated cells may occur, but they are mostly gathered to form islets. Cell surfaces exhibit microvilli. Cells are interconnected by means of microvilli and of structures similar to the epithelial "terminal bars." The cells line spaces and canaliculi similar to bile canaliculi. The cytoplasm is poorly di...

Some ultrastructural features of Yoshida ascites hepatoma.

Multiplication of influenza virus in the Ehrlich ascites carcinoma.

The effect of viruses on malignant tumors has been examined by a number of investigators (9). With the conversion of solid tumors into ascites form (8), however, it has become possible to carry out a more definitive study of the growth of viruses in cancer cells. The present communication deals with the normal growth characteristics of a hyperdiploid line of the Ehrlich ascites carcinoma of the...

Establishment of metastatic growth by Yoshida Ascites

Establishment of metastatic growth by Yoshida Ascites Hepatoma 7974 in the chick embryo liver has been studied with light and electron microscopy. Tumor cells lie as emboli within the sinusoids for the first 24 hr and then begin to divide and invade the parenchyma by 48 hr after inoculation. At this time, tumor cells are seen to extend pseudopodia beneath the endothelium, which in many instance...

Metabolism of phospholipids in Ehrlich ascites tumor.

of cancer cells may be related to the characteristics of the cell surface membranes (i, 7, 43). For example, Coman and his associates have drawn attention to the importance of such properties of the cell surface as adhesiveness(6, 31) and stickiness (8). Since it is now known that lipids, and in particular phospholipids, are essential components of all cell membranes, including both the plasma ...